BORS Revalidation Session

10.30am – 12pm BST, 17 September 2024 ‐ 1 hour 30 mins

Room: Hall 10

Specialist Society

Injectables and Cell Therapies for Cartilage Repair/Osteoarthritis: Clinicians and Scientists Working Together to Understand Mechanism and Improve Stratification

Chair: Ines Reichart, Co-Chair: Karina Wright

This session will explore the current injectable and surgical approaches used in the treatment of cartilage injuries and osteoarthritis, with a particular focus in the knee:

Interventions covered will include hydrogels, blood and bone marrow derived biologics as well as advanced therapy medicinal products (ATMPs), including autologous chondrocyte implantation (ACI).

An understanding of the changing regulatory landscape pertinent to these interventions is key and will be reviewed.

The process and challenges of undertaking a clinical trial to evaluate efficacy will be explored.

Exemplars describing how clinicians and scientists can work together to better understand mechanism and improve stratification of treatments will be presented.

Agenda:
 

10:30 – 10:50  Introduction  Professor David Johnson

10:50 – 11:10  Current Surgical Options and Injections  Paul Jermin

11:10 – 11:30  Trials and Tribulations  James Murray

11:30 – 11:50  Scientific Study of Mechanism and Stratification  Professor Karina Wright

11:50 – 12:00  Open Discussion and Round-Up  All