Studies Funded through BOSRC Support
The BOSRC has secured over £11million in funding for orthopaedic studies, including 5 large multicentre trials. The list below details the studies funded so far through this initiative.
OPAL
Full Title: Development of an occupational advice intervention for patients undergoing lower limb arthroplasty
Chief Investigator: Mr Paul Baker, South Tees Hospitals NHS Foundation Trust
Funding Details: NIHR HTA Commissioned, £567,975, (July 2016)
Surgical Rib Fracture Fixation
Full Title: Rib Fracture Fixation
Chief Investigator: Helen Ingoe
Funding Details: Orthopaedic Research UK Fellowship
PRESTO
Full Title: Surgical fixation versus non-operative management for patients with stable thoracolumbar fractures: a feasibility study
Chief Investigator: Mr Arun Ranganathan, Barts Health NHS Trust
Funding Details: NIHR HTA Commissioned, £452,636, (September 2017)
ACTIVE
Full Title: External frame versus internal locking plate for articular pilon fracture fixation in adult patients: a multi-centre randomised controlled trial
Chief Investigator: Mr Hemant Sharma, Hull and East Yorkshire Hospitals NHS Trust
Funding Details: NIHR HTA Researcher-led, £1,581,348,(September 2017)
QIST
Full Title: Scaling Up Quality Improvement for Surgical Teams: avoiding surgical site infection and anaemia at the time of surgery: a randomised controlled trial
Chief Investigator: Professor Mike Reed, Northumbria Healthcare NHS Foundation Trust
Funding Details: NHS Improvement; Northumbria Acute Care Collaboration Vanguard; Vifor Pharma; Schuelke, £321,266, (November 2017)
KREBS
Full Title: A randomised controlled trial of the effect of a two-layer compression bandage system on knee function following total knee arthroplasty
Chief Investigator: Professor Mike Reed, Northumbria Healthcare NHS Foundation Trust
Funding Details: 3M Healthcare, £201,484, (August 2016)
DISC
Full Title: A pragmatic multi-centre randomised controlled non-inferiority, cost-effectiveness trial comparing injections of collagenase into the cord to surgical correction in the treatment of moderate Dupuytren’s contracture in adult patients
Chief Investigator: Professor Joseph Dias, University Hospitals of Leicester NHS Trust
Funding Details: NIHR HTA Commissioned, £1,942,078, (November 2016)
ProFHER-2
Full Title: Effectiveness and cost-effectiveness of reverse shoulder arthroplasty versus hemiarthroplasty versus non-surgical care for acute 3 and 4 part fractures of the proximal humerus in older adults – the ProFHER 2 randomised controlled trial
Chief Investigator: Professor Amar Rangan, South Tees Hospitals NHS Foundation Trust
Funding Details: NIHR HTA Commissioned, £2,287,576, (December 2017)
L1FE
Full Title: Lateral Compression Type-1 Fracture Fixation in the Elderly: a Randomised Controlled Trial
Chief Investigator: Mr Peter Bates, Barts Health NHS Trust
Funding Details: NIHR HTA Researcher-led, £2,000,330, (October 2018)