Studies Funded through BOSRC Support
The BOSRC has secured over £11million in funding for orthopaedic studies, including 5 large multicentre trials. The list below details the studies funded so far through this initiative.
OPAL
![OPAL Logo.png](https://www.boa.ac.uk/static/derivatives/200x106_highestperformance_/cd6b13ce-4218-459d-86b1003ce6dd0d4c.png)
Full Title: Development of an occupational advice intervention for patients undergoing lower limb arthroplasty
Chief Investigator: Mr Paul Baker, South Tees Hospitals NHS Foundation Trust
Funding Details: NIHR HTA Commissioned, £567,975, (July 2016)
Surgical Rib Fracture Fixation
Full Title: Rib Fracture Fixation
Chief Investigator: Helen Ingoe
Funding Details: Orthopaedic Research UK Fellowship
PRESTO
![Presto Logo.png](https://www.boa.ac.uk/static/derivatives/200x112_highestperformance_/f22d4ad8-981c-4389-ac853dd2436b6af0.png)
Full Title: Surgical fixation versus non-operative management for patients with stable thoracolumbar fractures: a feasibility study
Chief Investigator: Mr Arun Ranganathan, Barts Health NHS Trust
Funding Details: NIHR HTA Commissioned, £452,636, (September 2017)
ACTIVE
![Active Logo.png](https://www.boa.ac.uk/static/derivatives/200x65_highestperformance_/2a2fffa9-89c9-45a4-8a3481e8f7ea2bec.png)
Full Title: External frame versus internal locking plate for articular pilon fracture fixation in adult patients: a multi-centre randomised controlled trial
Chief Investigator: Mr Hemant Sharma, Hull and East Yorkshire Hospitals NHS Trust
Funding Details: NIHR HTA Researcher-led, £1,581,348,(September 2017)
QIST
![QIST Logo.png](https://www.boa.ac.uk/static/derivatives/200x94_highestperformance_/5906cc9a-77ff-47e9-a1a7067e8e768d96.png)
Full Title: Scaling Up Quality Improvement for Surgical Teams: avoiding surgical site infection and anaemia at the time of surgery: a randomised controlled trial
Chief Investigator: Professor Mike Reed, Northumbria Healthcare NHS Foundation Trust
Funding Details: NHS Improvement; Northumbria Acute Care Collaboration Vanguard; Vifor Pharma; Schuelke, £321,266, (November 2017)
KREBS
![KREBS Logo.png](https://www.boa.ac.uk/static/derivatives/200x52_highestperformance_/a80c4298-1465-4d75-a3de2231405cc96c.png)
Full Title: A randomised controlled trial of the effect of a two-layer compression bandage system on knee function following total knee arthroplasty
Chief Investigator: Professor Mike Reed, Northumbria Healthcare NHS Foundation Trust
Funding Details: 3M Healthcare, £201,484, (August 2016)
DISC
![DISC Logo.png](https://www.boa.ac.uk/static/derivatives/200x114_highestperformance_/1c2d1eb4-0089-45dc-90a6549fe323c984.png)
Full Title: A pragmatic multi-centre randomised controlled non-inferiority, cost-effectiveness trial comparing injections of collagenase into the cord to surgical correction in the treatment of moderate Dupuytren’s contracture in adult patients
Chief Investigator: Professor Joseph Dias, University Hospitals of Leicester NHS Trust
Funding Details: NIHR HTA Commissioned, £1,942,078, (November 2016)
ProFHER-2
![ProPHER 2 Logo.png](https://www.boa.ac.uk/static/derivatives/200x168_highestperformance_/95200009-3b90-4ce7-856ed9d3ed82ece3.png)
Full Title: Effectiveness and cost-effectiveness of reverse shoulder arthroplasty versus hemiarthroplasty versus non-surgical care for acute 3 and 4 part fractures of the proximal humerus in older adults – the ProFHER 2 randomised controlled trial
Chief Investigator: Professor Amar Rangan, South Tees Hospitals NHS Foundation Trust
Funding Details: NIHR HTA Commissioned, £2,287,576, (December 2017)
L1FE
Full Title: Lateral Compression Type-1 Fracture Fixation in the Elderly: a Randomised Controlled Trial
Chief Investigator: Mr Peter Bates, Barts Health NHS Trust
Funding Details: NIHR HTA Researcher-led, £2,000,330, (October 2018)